Vigabatrin monotherapy in resistant neonatal seizures

نویسندگان

  • P. S. Baxter
  • D. Gardner-Medwin
  • D. D. Barwick
  • P. Ince
  • J. Livingston
  • D. Murdoch-Eaton
چکیده

Seizures in a term infant with Ohtahara syndrome, associated with polymicrogyria, and a pre-term neonate with similar clinical features, failed to respond to conventional anticonvulsants, but were controlled with vigabatrin monotherapy. Another infant with Aicardi syndrome improved with vigabatrin. Autopsy in the first infant showed no evidence of intramyelinic oedema. The developmental outcome in the two survivors was better than expected for their condition.

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عنوان ژورنال:
  • Seizure

دوره 4  شماره 

صفحات  -

تاریخ انتشار 1995